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Endometriosis: The Power of Anti-Inflammatory Nutrition and Natural Support

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When it comes to managing endometriosis, most conversations revolve around hormones. While hormonal treatments remain the conventional approach, mounting evidence — and years of clinical observation — show that endometriosis is fundamentally an inflammatory and immune condition.

This means real relief starts with addressing what’s happening in the immune system — and one of the most powerful (and underused) tools we have is nutrition.

Here’s what the research and clinical experience reveal about the foods and supplements that can make a real difference for women living with endometriosis.

1. Avoid Dairy — Especially A1 Casein

Conventional dairy contains a protein called A1 casein, which has been shown to disrupt immune function and stimulate the release of inflammatory cytokines. For women with endometriosis, this kind of immune activation can worsen symptoms and increase pain.

In my clinical work, I’ve found that removing dairy — especially A1 dairy — is often the single most effective dietary change a woman can make. Symptom improvements can include reduced pain, better digestion, and more stable cycles.

A quick note on A1 vs A2:
  • A1 casein is found in most supermarket dairy products.
  • A2 milk (from goats, sheep, and certain breeds of cows) may be less inflammatory, but many still benefit from avoiding all dairy completely — at least initially.

2. Consider Removing Gluten (and Possibly Eggs)

Gluten is another common immune disruptor. It stimulates inflammatory cytokines and contributes to a condition called intestinal permeability, or “leaky gut,” which is increasingly associated with autoimmune and inflammatory diseases — including endometriosis.

One clinical study showed that 75% of women with endometriosis improved after 12 months on a gluten-free diet.

Eggs can also be problematic for some women. While not everyone with endo needs to eliminate eggs, many notice symptom relief when they do — likely due to immune reactivity to egg proteins.

3. Berberine: Anti-Inflammatory + Gut-Healing

Berberine is a natural plant compound that offers multiple benefits for endometriosis:

  • Reduces inflammation
  • Repairs intestinal permeability
  • Improves immune regulation
  • Acts as an antimicrobial, targeting the bacterial toxin LPS, which may play a role in endometriosis development

Berberine can be a powerful addition to a natural protocol — but it’s not for everyone.
Caution: Do not take if pregnant or breastfeeding, and avoid long-term use unless under practitioner supervision.

4. N-Acetyl Cysteine (NAC): Clinically Proven Relief

NAC is a powerful antioxidant and anti-inflammatory supplement — and it’s shown incredible promise in treating endometriosis.

In a recent clinical trial, 24 out of 47 women who were scheduled for laparoscopy cancelled their surgeries after taking NAC due to a significant reduction in pain, the disappearance of endometriomas, or even spontaneous pregnancy.

Unlike hormonal treatments, NAC has no significant side effects, making it a safe and effective option for long-term use.

5. Turmeric (Curcumin): Oestrogen-Modulating & Lesion-Shrinking

Turmeric, specifically its active compound curcumin, has strong anti-inflammatory and hormone-modulating properties. It works by:

  • Reducing the inflammatory protein NF-kappa B
  • Blocking oestrogen’s overstimulating effect on endometrial tissue
  • Shrinking the size and activity of endometriosis lesions

Turmeric is most effective when taken in capsule or tablet form, ideally in a high-potency, bioavailable formulation.

6. Zinc: Small Nutrient, Big Impact

Zinc is often overlooked, but it plays a vital role in immune health and inflammation control.

Women with endometriosis are frequently deficient in zinc, and this can contribute to symptoms like pain, fatigue, and poor gut function.

Zinc helps by:

  • Repairing intestinal permeability
  • Regulating immune function
  • Reducing prostaglandins (which contribute to pain and inflammation)

Including zinc-rich foods (like oysters, pumpkin seeds, and beef) or a quality supplement can be an important piece of your endo-healing plan.

Turmeric is most effective when taken in capsule or tablet form, ideally in a high-potency, bioavailable formulation.

7. Homeopathic Oestrogen

I use homeopathics daily in the clinic with such good results that even bragging about them doesn’t do them justice.

Research also supports the use of potentised oestrogen. A 2017 study showed that Homeopathic oestrogen at a dose of 3 drops twice daily for 24 weeks was significantly more effective than placebo for reducing endometriosis-associated pelvic pain.

Final Thoughts: Treat the Root, Not Just the Symptoms

While hormonal suppression can offer temporary relief, it doesn’t address the underlying immune dysfunction driving endometriosis. The good news? Diet and targeted natural therapies can help reduce inflammation, modulate immune responses, and support long-term healing — without the side effects of medication.

If you’re living with endometriosis, it’s worth exploring these tools with the support of a qualified practitioner who understands the full-body nature of this condition.

This article is for informational purposes only and not intended as medical advice. Always consult with your healthcare provider before beginning any new treatment.

References:

https://pmc.ncbi.nlm.nih.gov/articles/PMC3662115

https://academic.oup.com/jid/article-abstract/203/11/1602/863485?redirectedFrom=fulltext

https://pubmed.ncbi.nlm.nih.gov/24166511

https://pubmed.ncbi.nlm.nih.gov/23334113

https://pubmed.ncbi.nlm.nih.gov/22227273

https://pubmed.ncbi.nlm.nih.gov/25864256

https://pmc.ncbi.nlm.nih.gov/articles/PMC3662115

https://www.sciencedirect.com/science/article/abs/pii/S030121151730060X

blog Post by Paige Cowley Naturopath and Nutritionist

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